You do realize you have a gigantic range of costs there, right?

AFM is literally triple the cost of WW, with the other two falling in between, just in case you didn't know that already. There is also a huge range in play styles, so it's tough to give recommendations without knowing what you prefer in a game. You have one of the fastest, most flowing games in AFM, and one of the most stop-and-go games in TSPP with the other two falling in between. You really have apples vs oranges vs bananas vs avacodos here!
As for the games themselves, if everything else was equal I would pick AFM no questions asked. It is an amazing game. The only thing that holds me back from buying one is the price. I wish I would have bought one a few years ago before they skyrocketed. As much as I love the game, I don't see it being worth what they go for now. If you are looking for depth, this wouldn't be the top of what you listed. Actually it's probably 3rd in depth, though I'm not super familiar with FG's ruleset. There is plenty to do, but it isn't really a deep game...it's pretty straight-forward.
Whirlwind is a very close second for me. I adore that game...it's a classic through and through. The price is also very reasonable. However, it has by far the smallest ruleset of the games you listed. It has plenty of depth for its era, but can't compete in rule complexity with the others, which are much newer with more technology in them. That doesn't stop it from being a great game though, and for the price you really can't go wrong.
The other two are about equal for me, and neither are really high on my favorites list. I probably prefer the gameplay of FG a bit, but I like the theme of TSPP much more. TSPP is known as being one of the deepest games ever made, if not THE deepest. You will most likely never see everything there is to see in this game. I believe there are only a handful of people in the world who have ever seen the wizard mode (with the glass on). You gotta respect that. However I find the playfield to be a bit of a mess and have a hard time getting into the game.
Family Guy also does not have my favorite playfield design, though I do enjoy parts of it. The mini-playfield is genius and a lot of fun. There seems to be a lot of depth, but not on par with Simpsons. The rules are fun though, and it is enjoyable to bat the ball around. If I liked the theme more, I could see really getting into this one. I haven't played a Shrek (which is the same game different theming), but I love that theme, so I could see falling in love with that one.
So I'd say if you are going for depth, TSPP is the clear winner. If you are going for pure fun and excitement and money is no object, AFM is the way to go. If you want an all time classic and are willing to sacrifice depth for fun and character at a budget price, WW wins. I think FG loses this one unless you are a huge fan of the show and are willing to go middle of the road in rules, price, and fun factor.
So all that said, and it was probably no help at all...