It was fine before you cleaned it, and isn't now. While it could be a component issue, most likely it's something you have put your hands on. Start there. If you have to go further than that, *do not* make assumptions about what you touched and didn't touch. That's a great way to waste hours troubleshooting. Assume ALL connections are suspect even if you know you put it back right. Check the schematics, check the cable, match up the right pins. Triple check and make sure you didn't put a connector on backwards. Or that the back of a circuit board isn't now touching something. Or that a +V/gnd wire didn't fall/break off and is resting where it shouldn't be. Especially check coin mech bulbs and switches for contact shorts. Blowing the dust off can on occasion cause a board to die from static, but it doesn't generally cause short circuits and blown fuses. You didn't use a vacuum did you?
Still haven't solved it, start labeling cables and breaking things down into sections.
First, disconnect the monitor (power and data) and power up. Does that change things? If not, leave it disco'd.
Next, disconnect the controls and power up. Does that change things? If not, leave them disco'd.
Next, disconnect the game from the PS (remember to LABEL) and check your voltages at the PS. Are they good? Does it blow a fuse? If so, suspect the supply, if not, suspect the board.
Move into the boards. Is there an audio or video board that can be disconnected. Label connection orientation and try disconnecting those one at a time. Does that change things? If not, leave it disco'd and move on.
Keep splitting and testing until you have identified the sub-system that is the offender. Once you have identified the problem child, start examining it closely for bent pins & components, ribbon cables that are off by one position, etc. If you've got a puller and you're comfortable, pull the socketed chips, clean the pins and re-seat them. Keep going through each item until something changes. And keep good notes....