No, the tube is a vacuum - no air inside. The cigarette tar does get all over the face of the tube though, and I've seen it on there so tough that most cleaners wouldn't touch it. You usually need something with ammonia in it (some versions of Windex), or straight isopropyl alcohol to clean some of that nasty gunk off the face of the tube. One time I even had to scrape it off with a razor.
-Ian